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Ligand · 2MR

2MR · N3, N4-dimethylarginine

2MR, N3, N4-dimethylarginine (C8 H18 N4 O2, 202.2 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (2 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found with…

Component
2MR
Formula
C8 H18 N4 O2
Class
ligand
Structures
2
PDB entries
2

Binding sites

2MR in 2 structures; the first of them:

  • 6AX3 · Complex structure of JMJD5 and Symmetric Dimethyl-Arginine (SDMA) · 2MR A501 · binds GLU238, TYR243, TYR272, ALA274, GLN275, TRP310, ILE317, SER318 and 4 more
  • 6OI2 · Crystal structure of human WDR5 in complex with symmetric dimethyl-L-arginine · 2MR A407 · binds SER49, SER91, ASP92, PHE133, CYS134, SER175, SER218, PHE219 and 6 more

Residues it binds most

SER 2, ILE 2, PHE 1, TYR 2, ASP 2, CYS 1, TRP 1, ALA 1, GLN 1, GLU 1 (residue and the binding sites it lines).

Found with

  • AKG · 2-oxoglutaric acid
  • ZN · Zinc ion
  • SO4 · Sulfate ion
  • GOL · Glycerol

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