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Ligand · 2KR

2KR · N-[4-(2-methoxy-3H-imidazo[4,5-b]pyridin-3-yl)phenyl]-5-methylpyridin-2-amine

2KR, N-[4-(2-methoxy-3H-imidazo[4,5-b]pyridin-3-yl)phenyl]-5-methylpyridin-2-amine (C19 H17 N5 O, 331.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the…

Component
2KR
Formula
C19 H17 N5 O
Class
ligand
Structures
2
PDB entries
1

Binding sites

2KR in 2 structures; the first of them:

  • 4P1R · Crystal Structure of PDE10A with Imidazo[4,5-b]pyridines as Potent and Selective… · 2KR A1020 · binds LEU625, LEU665, SER667, VAL668, ILE682, TYR683, PHE686, PRO702 and 7 more
  • 4P1R · Crystal structure of PDE10A with IMIDAZO[4,5-B]PYRIDINES as potent and selective… · 2KR A1020 · binds LEU625, LEU665, SER667, VAL668, ILE682, TYR683, PHE686, PRO702 and 7 more

Residues it binds most

LEU 4, PHE 4, VAL 4, GLN 4, GLU 4, GLY 4, ILE 4, LYS 4, MET 4, PRO 4 (residue and the binding sites it lines).

Found with

  • ZN · Zinc ion
  • SO4 · Sulfate ion
  • GOL · Glycerol

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