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Ligand · 2KD

2KD · 6-(3-chlorophenyl)-2-{[(2S)-3-(4-hydroxyphenyl)-1-methoxy-1-oxopropan-2-yl]carbamoyl}quinoline-4-carboxylic acid

2KD, 6-(3-chlorophenyl)-2-{[(2S)-3-(4-hydroxyphenyl)-1-methoxy-1-oxopropan-2-yl]carbamoyl}quinoline-4-carboxylic acid (C27 H21 Cl N2 O6, 504.9 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding…

Component
2KD
Formula
C27 H21 Cl N2 O6
Class
ligand
Structures
2
PDB entries
1

Binding sites

2KD in 2 structures; the first of them:

  • 4NJ3 · Modulating the interaction between CDK2 and Cyclin A with a Quinoline-based inhibitor · 2KD A301 · binds ILE10, TYR15, VAL18, ALA31, LYS33, LEU55, LEU58, ILE63 and 17 more
  • 4NJ3 · Modulating the interaction between CDK2 and cyclin a with a quinoline- based inhibitor · 2KD A301 · binds ILE10, TYR15, VAL18, ALA31, LYS33, LEU55, LEU58, ILE63 and 17 more

Residues it binds most

LEU 2, ALA 2, PHE 2, VAL 2, ILE 2, ASN 2, ASP 2, GLN 2, GLU 2, GLY 2 (residue and the binding sites it lines).

Found with

  • ACE · Acetyl group

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