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Ligand · 2K0

2K0 · [2-chloro-5-(hydroxymethyl)phenyl]{5-[1-(piperidin-4-yl)-1H-pyrazol-4-yl]-1H-pyrrolo[2,3-b]pyridin-3-yl}methanone

2K0, [2-chloro-5-(hydroxymethyl)phenyl]{5-[1-(piperidin-4-yl)-1H-pyrazol-4-yl]-1H-pyrrolo[2,3-b]pyridin-3-yl}methanone (C23 H22 Cl N5 O2, 435.9 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding…

Component
2K0
Formula
C23 H22 Cl N5 O2
Class
ligand
Structures
2
PDB entries
1

Binding sites

2K0 in 2 structures; the first of them:

  • 4P90 · Crystal structure of the kinase domain of human PAK1 in complex with compound 15 · 2K0 A601 · binds ILE276, VAL284, ALA297, ILE298, LYS299, GLU315, VAL328, VAL342 and 8 more
  • 4P90 · Crystal structure of the kinase domain of human PAK1 in complex with compound 15 · 2K0 A601 · binds ILE276, VAL284, ALA297, ILE298, LYS299, GLU315, VAL328, VAL342 and 8 more

Residues it binds most

VAL 4, ILE 4, LEU 4, ASP 4, GLU 4, ALA 4, GLY 4, LYS 4, MET 4, THR 4 (residue and the binding sites it lines).

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