GL1X · GenesisL1 explorer

Ligand · 2JP

2JP · 4-(isoquinolin-3-ylamino)-4-oxobutanoic acid

2JP, 4-(isoquinolin-3-ylamino)-4-oxobutanoic acid (C13 H12 N2 O3, 244.2 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (2 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and…

Component
2JP
Formula
C13 H12 N2 O3
Class
ligand
Structures
2
PDB entries
2

Binding sites

2JP in 2 structures; the first of them:

  • 6YVX · Hif prolyl hydroxylase 2 (PHD2/ EGLN1) in complex with bicyclic bb-287 · 2JP A502 · binds MET299, TYR303, TYR310, HIS313, ASP315, ILE327, TYR329, LEU343 and 5 more
  • 6YW0 · Lysine-N,N-dimethylated hif prolyl hydroxylase 2 (PHD2/ EGLN1) in complex with bb-287 · 2JP A502 · binds TYR303, TYR310, HIS313, ASP315, ILE327, TYR329, LEU343, HIS374 and 3 more

Residues it binds most

TYR 2, HIS 2, ALA 2, ARG 2, ASP 2, ILE 2, LEU 2, VAL 2, MET 1, TRP 1 (residue and the binding sites it lines).

Found with

  • BCT · Bicarbonate ion
  • FE · Fe (III) ion
  • MN · Manganese (II) ion

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.