2J8 · (4S,11S,18S)-4,11,18-tri(propan-2-yl)-6,13,20-triselena-3,10,17,22,23,24-hexaazatetracyclo[17.2.1.1~5,8~.1~12,15~]tetracosa-1(21),5(24),7,12(23),14,19(22)-hexaene-2,9,16-trione

Binding sites

2J8 in 4 structures; the first of them:

• 3G61 · Structure of P-glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding · 2J8 A6001 · binds LEU300, TYR303, PHE339, GLN721, PHE724, LEU758, PHE974, VAL978 and 5 more
• 4M2T · Corrected Structure of Mouse P-glycoprotein bound to QZ59-SSS · 2J8 A6001 · binds MET295, ALA298, PHE299, ILE302, TYR303, TYR306, LEU335, ILE336 and 8 more
• 3G61 · Structure of P-glycoprotein reveals a molecular basis for poly- specific drug binding · 2J8 A6001 · binds LEU300, TYR303, PHE339, GLN721, PHE724, LEU758, PHE974, VAL978 and 5 more
• 4M2T · Corrected structure of mouse P-glycoprotein bound to QZ59-sss · 2J8 A6001 · binds MET295, ALA298, PHE299, ILE302, TYR303, TYR306, LEU335, ILE336 and 8 more

Residues it binds most

PHE 16, LEU 16, MET 16, TYR 16, GLN 8, ILE 10, ALA 10, VAL 12, SER 10, GLY 4 (residue and the binding sites it lines).