GL1X · GenesisL1 explorer

Ligand · 2IW

2IW · 4-[(3aR,4S,7R,7aS)-1,3-dioxo-1,3,3a,4,7,7a-hexahydro-2H-4,7-methanoisoindol-2-yl]-N-(4-methylquinolin-8-yl)benzamide

2IW, 4-[(3aR,4S,7R,7aS)-1,3-dioxo-1,3,3a,4,7,7a-hexahydro-2H-4,7-methanoisoindol-2-yl]-N-(4-methylquinolin-8-yl)benzamide (C26 H21 N3 O3, 423.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding…

Component
2IW
Formula
C26 H21 N3 O3
Class
ligand
Structures
2
PDB entries
1

Binding sites

2IW in 2 structures; the first of them:

  • 4DVI · Crystal structure of Tankyrase 1 with IWR2 · 2IW A1402 · binds HIS1184, GLY1185, SER1186, PHE1188, ALA1191, ILE1192, LYS1195, GLY1196 and 11 more
  • 4DVI · Crystal structure of tankyrase 1 with IWR2 · 2IW A1402 · binds HIS1184, GLY1185, SER1186, PHE1188, ALA1191, ILE1192, LYS1195, GLY1196 and 11 more

Residues it binds most

GLY 4, ILE 4, TYR 4, PHE 4, ALA 4, HIS 4, ASP 4, LYS 4, SER 4 (residue and the binding sites it lines).

Found with

  • ZN · Zinc ion

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