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Ligand · 2I8

2I8 · 3-(1~{H}-indazol-3-yl)-~{N}-[[1-(2-methylphenyl)-1,2,3-triazol-4-yl]methyl]-5-(propanoylamino)benzamide

2I8, 3-(1~{H}-indazol-3-yl)-~{N}-[[1-(2-methylphenyl)-1,2,3-triazol-4-yl]methyl]-5-(propanoylamino)benzamide (C27 H25 N7 O2, 479.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its…

Component
2I8
Formula
C27 H25 N7 O2
Class
ligand
Structures
2
PDB entries
1

Binding sites

2I8 in 2 structures; the first of them:

  • 7OVN · Protein kinase MKK7 in complex with tolyl-substituted indazole · 2I8 A501 · binds MET142, GLY143, SER144, LYS152, ALA163, VAL196, MET212, GLU213 and 10 more
  • 7OVN · Protein kinase MKK7 in complex with tolyl-substituted indazole · 2I8 A501 · binds MET142, SER144, LYS152, ALA163, MET212, GLU213, LEU214, MET215 and 8 more

Residues it binds most

MET 2, CYS 2, LEU 2, LYS 2, SER 2, GLY 2, ALA 2, ASP 2, GLU 2, THR 2 (residue and the binding sites it lines).

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