Ligand · 2HY
2HY · 2-hydroxyethyl (4R)-4-(4-cyanophenyl)-6-methyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-1,2,3,4-tetrahydropyrimidine-5-carboxylate
2HY, 2-hydroxyethyl (4R)-4-(4-cyanophenyl)-6-methyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-1,2,3,4-tetrahydropyrimidine-5-carboxylate (C22 H18 F3 N3 O4, 445.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry).…
- Component
- 2HY
- Formula
- C22 H18 F3 N3 O4
- Class
- ligand
- Structures
- 2
- PDB entries
- 1
Binding sites
2HY in 2 structures; the first of them:
- 3Q77 · Structure of human neutrophil elastase in complex with a dihydropyrimidone inhibitor · 2HY A500 · binds HIS57, TYR94, ASP95, PRO98, LEU99B, LEU100, ASP102, VAL190 and 10 more
- 3Q77 · Structure of human neutrophil elastase in complex with a dihydropyrimidone inhibitor · 2HY A500 · binds HIS57, TYR94, ASP95, PRO98, LEU99B, LEU100, ASP102, VAL190 and 10 more
Residues it binds most
ASP 2, ALA 2, CYS 2, LEU 2, PHE 2, SER 2, VAL 2, HIS 2, PRO 2, TYR 2 (residue and the binding sites it lines).
Found with
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