GL1X · GenesisL1 explorer

Ligand · 2H7

2H7 · 4-fluoro-N-({1-[(2R)-4-(hydroxyamino)-1-(naphthalen-2-yl)-4-oxobutan-2-yl]-1H-1,2,3-triazol-4-yl}methyl)benzamide

2H7, 4-fluoro-N-({1-[(2R)-4-(hydroxyamino)-1-(naphthalen-2-yl)-4-oxobutan-2-yl]-1H-1,2,3-triazol-4-yl}methyl)benzamide (C24 H22 F N5 O3, 447.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding…

Component
2H7
Formula
C24 H22 F N5 O3
Class
ligand
Structures
2
PDB entries
1

Binding sites

2H7 in 2 structures; the first of them:

  • 4NXO · Crystal Structure of Insulin Degrading Enzyme in complex with BDM44768 · 2H7 A1102 · binds HIS108, GLN111, HIS112, PHE115, SER128, SER138, ASN139, ALA140 and 9 more
  • 4NXO · Crystal structure of insulin degrading enzyme in complex with BDM44768 · 2H7 A1102 · binds HIS108, GLN111, HIS112, PHE115, SER128, SER138, ASN139, ALA140 and 9 more

Residues it binds most

PHE 4, SER 4, GLU 4, HIS 4, ALA 4, ARG 4, ASN 4, GLN 4, ILE 4, TYR 4 (residue and the binding sites it lines).

Found with

  • ZN · Zinc ion
  • 1PE · Pentaethylene glycol
  • DIO · 1,4-diethylene dioxide
  • EDO · 1,2-ethanediol
  • EPE · 4-(2-hydroxyethyl)-1-piperazine ethanesulfonic acid
  • PEG · Di(hydroxyethyl)ether

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.