GL1X · GenesisL1 explorer

Ligand · 2FR

2FR · 3-[3-(3-methyl-6-{[(1S)-1-phenylethyl]amino}-1H-pyrazolo[4,3-c]pyridin-1-yl)phenyl]propanamide

2FR, 3-[3-(3-methyl-6-{[(1S)-1-phenylethyl]amino}-1H-pyrazolo[4,3-c]pyridin-1-yl)phenyl]propanamide (C24 H25 N5 O, 399.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues…

Component
2FR
Formula
C24 H25 N5 O
Class
ligand
Structures
2
PDB entries
1

Binding sites

2FR in 2 structures; the first of them:

  • 3DBC · Crystal structure of an activated (Thr->Asp) Polo-like kinase 1 (Plk1) catalytic domain… · 2FR A313 · binds LEU45, GLY46, LYS47, GLY48, ALA51, CYS53, ALA66, LYS68 and 12 more
  • 3DBC · Crystal structure of an activated (thr->asp) polo-like kinase 1 (PLK1) catalytic domain… · 2FR A313 · binds LEU45, GLY46, LYS47, GLY48, ALA51, CYS53, ALA66, LYS68 and 12 more

Residues it binds most

GLY 2, ALA 2, ARG 2, CYS 2, GLU 2, LEU 2, LYS 2, ASP 2, ILE 2, PHE 2 (residue and the binding sites it lines).

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.