Ligand · 2FD
2FD · 5-(6-amino-2-fluoro-purin-9-yl)-2-hydroxymethyl-tetrahydro-furan-3-ol
2FD, 5-(6-amino-2-fluoro-purin-9-yl)-2-hydroxymethyl-tetrahydro-furan-3-ol (C10 H12 F N5 O3, 269.2 g/mol), in the MolNFT structures on GenesisL1: bound in 6 records (3 PDB entries). Every binding site with its residues within 4.5 Å, the…
- Component
- 2FD
- Formula
- C10 H12 F N5 O3
- Class
- ligand
- Structures
- 6
- PDB entries
- 3
Binding sites
2FD in 6 structures; the first of them:
- 1PKE · Crystal Structure of E. coli purine nucleoside phosphorylase complexed with… · 2FD A446 · binds MET64, ARG87, SER90, CYS91, GLY92, ALA156, PHE159, VAL178 and 6 more
- 1Z34 · Crystal structure of Trichomonas vaginalis purine nucleoside phosphorylase complexed with… · 2FD A300 · binds GLY63, MET64, ARG87, THR90, CYS91, GLY92, THR156, PHE159 and 6 more
- 3GGS · Human purine nucleoside phosphorylase double mutant E201Q,N243D complexed with… · 2FD A300 · binds SER33, HIS86, TYR88, ALA116, ALA117, GLY118, VAL195, PHE200 and 9 more
- 1PKE · Crystal structure of E. COLI purine nucleoside phosphorylase complexed with… · 2FD A446 · binds MET64, ARG87, SER90, CYS91, GLY92, ALA156, PHE159, VAL178 and 6 more
- 1Z34 · Crystal structure of trichomonas vaginalis purine nucleoside phosphorylase complexed with… · 2FD A300 · binds GLY63, MET64, ARG87, THR90, CYS91, GLY92, THR156, PHE159 and 6 more
- 3GGS · Human purine nucleoside phosphorylase double mutant E201Q,N243D complexed with… · 2FD A300 · binds SER33, HIS86, TYR88, ALA116, ALA117, GLY118, VAL195, PHE200 and 9 more
Residues it binds most
VAL 14, GLY 16, MET 14, PHE 16, SER 14, ALA 12, GLU 8, ASP 12, THR 8, ARG 8 (residue and the binding sites it lines).
Found with
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