Ligand · 2FA
2FA · 2-(6-amino-2-fluoro-purin-9-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diol
2FA, 2-(6-amino-2-fluoro-purin-9-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diol (C10 H12 F N5 O4, 285.2 g/mol), in the MolNFT structures on GenesisL1: bound in 14 records (7 PDB entries). Every binding site with its residues within 4.5 Å…
- Component
- 2FA
- Formula
- C10 H12 F N5 O4
- Class
- ligand
- Structures
- 14
- PDB entries
- 7
Binding sites
2FA in 14 structures; the first of them:
- 1PK9 · Crystal Structure of E. coli purine nucleoside phosphorylase complexed with… · 2FA A306 · binds MET64, ARG87, SER90, CYS91, GLY92, ALA156, PHE159, VAL178 and 6 more
- 1Z35 · Crystal structure of Trichomonas vaginalis purine nucleoside phosphorylase complexed with… · 2FA A300 · binds GLY63, MET64, ARG87, THR90, CYS91, GLY92, THR156, PHE159 and 6 more
- 2PKK · Crystal structure of M tuberculosis Adenosine Kinase complexed with 2-fluro adenosine · 2FA A501 · binds SER8, ALA10, ASP12, GLY47, GLY48, VAL49, ASN52, PHE102 and 10 more
- 2ZJ0 · Crystal structure of Mycobacterium tuberculosis S-Adenosyl-L-homocysteine hydrolase in… · 2FA A500 · binds LEU68, HIS69, THR71, GLN73, THR74, ASP156, GLU218, THR219 and 11 more
- 4DAN · Crystal structure of the hexameric purine nucleoside phosphorylase from Bacillus subtilis… · 2FA A301 · binds MET64, ARG87, SER90, CYS91, GLY92, ALA156, PHE159, VAL177 and 8 more
- 4DC3 · Adenosine kinase from Schistosoma mansoni in complex with 2-fluoroadenosine · 2FA B401 · binds ASN14, LEU16, ASP18, ILE38, LEU40, GLY63, GLY64, ALA65 and 9 more
- 4UBE · Crystal structure of M tuberculosis adenosine kinase complexed with 2-fluro adenosine · 2FA A401 · binds SER8, ALA10, ASP12, GLY47, GLY48, VAL49, ASN52, PHE102 and 10 more
- 1PK9 · Crystal structure of E. COLI purine nucleoside phosphorylase complexed with… · 2FA A306 · binds MET64, ARG87, SER90, CYS91, GLY92, ALA156, PHE159, VAL178 and 6 more
- 1Z35 · Crystal structure of trichomonas vaginalis purine nucleoside phosphorylase complexed with… · 2FA A300 · binds GLY63, MET64, ARG87, THR90, CYS91, GLY92, THR156, PHE159 and 6 more
- 2PKK · Crystal structure of M tuberculosis adenosine kinase complexed with 2- fluro adenosine · 2FA A501 · binds SER8, ALA10, ASP12, GLY47, GLY48, VAL49, ASN52, PHE102 and 10 more
- 2ZJ0 · Crystal structure of mycobacterium tuberculosis S-adenosyl-L- homocysteine hydrolase in… · 2FA A500 · binds LEU68, HIS69, THR71, GLN73, THR74, ASP156, GLU218, THR219 and 11 more
- 4DAN · Crystal structure of the hexameric purine nucleoside phosphorylase from bacillus subtilis… · 2FA A301 · binds MET64, ARG87, SER90, CYS91, GLY92, ALA156, PHE159, VAL177 and 8 more
- 4DC3 · Adenosine kinase from schistosoma mansoni in complex with 2- fluoroadenosine · 2FA B401 · binds ASN14, LEU16, ASP18, ILE38, LEU40, GLY63, GLY64, ALA65 and 9 more
- 4UBE · Crystal structure of M tuberculosis adenosine kinase complexed with 2- fluro adenosine · 2FA A401 · binds SER8, ALA10, ASP12, GLY47, GLY48, VAL49, ASN52, PHE102 and 10 more
Residues it binds most
THR 16, GLY 26, ASP 24, MET 26, GLU 20, PHE 26, HIS 12, LEU 10, SER 18, ASN 14 (residue and the binding sites it lines).
Found with
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