2A4 · (2R,4S)-N,N'-bis[3-({4-[3-(aminomethyl)phenyl]piperidin-1-yl}carbonyl)phenyl]-4-hydroxy-2-(2-hydroxypropan-2-yl)-5,5-dimethyl-1,3-dioxolane-2,4-dicarboxamide

Binding sites

2A4 in 2 structures; the first of them:

• 4MPV · Human beta-tryptase co-crystal structure with (2R,4S)-N,N'-bis[3-({4-[3-(aminomethyl)pheny… · 2A4 A301 · binds TYR114, THR115, GLN117, ASP218, SER219, CYS220, GLN221, SER224 and 21 more
• 4MPV · Human beta-tryptase co-crystal structure with (2R,4S)-N,N'-BIS[3-({4… · 2A4 A301 · binds TYR114, THR115, GLN117, ASP218, SER219, CYS220, GLN221, SER224 and 21 more

Residues it binds most

GLY 2, SER 2, GLN 2, CYS 2, ASP 2, GLU 2, THR 2, TRP 2, VAL 2, TYR 2 (residue and the binding sites it lines).

Found with

• CL · Chloride ion
• SO4 · Sulfate ion
• MES · 2-(N-morpholino)-ethanesulfonic acid