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Ligand · 287

287 · 4-{[5-(methoxycarbamoyl)-2-methylphenyl]amino}-5-methyl-N-[(1S)-1-phenylethyl]pyrrolo[2,1-f][1,2,4]triazine-6-carboxamide

287, 4-{[5-(methoxycarbamoyl)-2-methylphenyl]amino}-5-methyl-N-[(1S)-1-phenylethyl]pyrrolo[2,1-f][1,2,4]triazine-6-carboxamide (C25 H26 N6 O3, 458.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every…

Component
287
Formula
C25 H26 N6 O3
Class
ligand
Structures
2
PDB entries
1

Binding sites

287 in 2 structures; the first of them:

  • 2RG6 · Phenylalanine pyrrolotriazine p38 alpha map kinase inhibitor compound 11J · 287 A501 · binds VAL30, VAL38, ALA51, VAL52, LYS53, GLU71, LEU75, ILE84 and 12 more
  • 2RG6 · Phenylalanine pyrrolotriazine P38 alpha MAP kinase inhibitor compound 11J · 287 A501 · binds VAL30, VAL38, ALA51, VAL52, LYS53, GLU71, LEU75, ILE84 and 12 more

Residues it binds most

LEU 4, ALA 4, VAL 2, ASP 2, ILE 4, MET 4, ASN 2, GLU 2, GLY 2, HIS 2 (residue and the binding sites it lines).

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