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Ligand · 24N

24N · 1-[(3~{R})-3-[4-azanyl-3-[1-[2,2-bis(fluoranyl)-2-phenyl-ethyl]-1,2,3-triazol-4-yl]pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]propan-1-one

24N, 1-[(3~{R})-3-[4-azanyl-3-[1-[2,2-bis(fluoranyl)-2-phenyl-ethyl]-1,2,3-triazol-4-yl]pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]propan-1-one (C23 H25 F2 N9 O, 481.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1…

Component
24N
Formula
C23 H25 F2 N9 O
Class
ligand
Structures
2
PDB entries
1

Binding sites

24N in 2 structures; the first of them:

  • 7OVJ · Protein kinase MKK7 in complex with difluoro-phenethyltriazole-substituted… · 24N A501 · binds MET142, GLY143, VAL150, ALA163, LYS165, ILE179, ASP182, LEU183 and 13 more
  • 7OVJ · Protein kinase MKK7 in complex with difluoro-phenethyltriazole- substituted… · 24N A501 · binds MET142, GLY143, ALA163, LYS165, ILE179, ASP182, LEU183, VAL196 and 10 more

Residues it binds most

LEU 2, MET 2, ASP 2, ILE 2, LYS 2, VAL 2, CYS 2, ALA 2, GLU 2, GLY 2 (residue and the binding sites it lines).

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