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Ligand · 222

222 · 2-(3-{(2-chloro-4-fluorophenyl)[1-(2-chlorophenyl)-6-oxo-1,6-dihydropyridazin-3-yl]amino}propyl)-1H-isoindole-1,3(2H)-dione

222, 2-(3-{(2-chloro-4-fluorophenyl)[1-(2-chlorophenyl)-6-oxo-1,6-dihydropyridazin-3-yl]amino}propyl)-1H-isoindole-1,3(2H)-dione (C27 H19 Cl2 F N4 O3, 537.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry).…

Component
222
Formula
C27 H19 Cl2 F N4 O3
Class
ligand
Structures
2
PDB entries
1

Binding sites

222 in 2 structures; the first of them:

  • 2I0H · The structure of p38alpha in complex with an arylpyridazi · 222 A400 · binds VAL30, TYR35, VAL38, ALA51, VAL52, LYS53, LEU75, ILE84 and 13 more
  • 2I0H · The structure of P38ALPHA in complex with an arylpyridazinone · 222 A400 · binds VAL30, TYR35, VAL38, ALA51, VAL52, LYS53, LEU75, ILE84 and 13 more

Residues it binds most

LEU 4, ALA 4, VAL 4, ASP 4, GLY 4, HIS 4, ILE 4, LYS 4, MET 4, SER 4 (residue and the binding sites it lines).

Found with

  • GOL · Glycerol

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