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Ligand · 1ZK

1ZK · 4-[(2R)-3-{[(1S,2S,3R,4S)-1-(cyclohexylmethyl)-2,3-dihydroxy-5-methyl-4-({(1S,2R)-2-methyl-1-[(pyridin-2-ylmethyl)carba moyl]butyl}carbamoyl)hexyl]amino}-2-{[(naphthalen-1-yloxy)acetyl]amino}-3-oxopropyl]-1H-imidazol-3-ium

1ZK, 4-[(2R)-3-{[(1S,2S,3R,4S)-1-(cyclohexylmethyl)-2,3-dihydroxy-5-methyl-4-({(1S,2R)-2-methyl-1-[(pyridin-2-ylmethyl)carba moyl]butyl}carbamoyl)hexyl]amino}-2-{[(naphthalen-1-yloxy)acetyl]amino}-3-oxopropyl]-1H-imidazol-3-ium (C45 H62 N7…

Component
1ZK
Formula
C45 H62 N7 O7 +1
Class
ligand
Structures
4
PDB entries
2

Binding sites

1ZK in 4 structures; the first of them:

  • 1HIV · Crystal structure of a complex of HIV-1 protease with a dihydroethylene-containing… · 1ZK A100 · binds ARG8, LEU23, ASP25, GLY27, ALA28, ASP29, ASP30, VAL32 and 23 more
  • 1IVP · The crystallographic structure of the protease from human immunodeficiency virus type 2… · 1ZK B100 · binds ARG8, LEU23, ASP25, GLY27, ALA28, ASP29, ASP30, VAL47 and 21 more
  • 1HIV · Crystal structure of a complex of HIV-1 protease with a dihydroethylene-containing… · 1ZK A100 · binds ARG8, LEU23, ASP25, GLY27, ALA28, ASP29, ASP30, VAL32 and 23 more
  • 1IVP · The crystallographic structure of the protease from human immunodeficiency virus type 2… · 1ZK B100 · binds ARG8, LEU23, ASP25, GLY27, ALA28, ASP29, ASP30, VAL47 and 21 more

Residues it binds most

ILE 4, GLY 4, ASP 4, VAL 4, LEU 4, ALA 4, ARG 4, PRO 4, PHE 4 (residue and the binding sites it lines).

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