GL1X · GenesisL1 explorer

Ligand · 1XZ

1XZ · 3-(2~{H}-indazol-3-yl)-~{N}-[[1-[(1~{R},2~{R})-2-methoxycyclohexyl]-1,2,3-triazol-4-yl]methyl]-5-(propanoylamino)benzamide

1XZ, 3-(2~{H}-indazol-3-yl)-~{N}-[[1-[(1~{R},2~{R})-2-methoxycyclohexyl]-1,2,3-triazol-4-yl]methyl]-5-(propanoylamino)benzamide (C27 H31 N7 O3, 501.6 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every…

Component
1XZ
Formula
C27 H31 N7 O3
Class
ligand
Structures
2
PDB entries
1

Binding sites

1XZ in 2 structures; the first of them:

  • 7OVL · Protein kinase MKK7 in complex with methoxycyclohexyl-substituted indazole · 1XZ A501 · binds MET142, GLY143, LYS152, VAL161, ALA163, VAL196, MET212, GLU213 and 9 more
  • 7OVL · Protein kinase MKK7 in complex with methoxycyclohexyl-substituted indazole · 1XZ A501 · binds MET142, GLY143, LYS152, VAL161, GLU213, LEU214, MET215, GLY216 and 6 more

Residues it binds most

MET 2, CYS 2, GLU 2, GLY 2, LEU 2, VAL 2, LYS 2, SER 2, THR 2, ALA 1 (residue and the binding sites it lines).

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