Ligand · 1XC
1XC · 6-({4-[(3,5-difluorophenyl)sulfonyl]benzyl}carbamoyl)-1-(5-O-phosphono-beta-D-ribofuranosyl)imidazo[1,2-a]pyridin-1-ium
1XC, 6-({4-[(3,5-difluorophenyl)sulfonyl]benzyl}carbamoyl)-1-(5-O-phosphono-beta-D-ribofuranosyl)imidazo[1,2-a]pyridin-1-ium (C26 H25 F2 N3 O10 P S +1, 640.5 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB…
- Component
- 1XC
- Formula
- C26 H25 F2 N3 O10 P S +1
- Class
- ligand
- Structures
- 4
- PDB entries
- 2
Binding sites
1XC in 4 structures; the first of them:
- 4L4L · Structural Analysis of a Phosphoribosylated Inhibitor in Complex with Human Nicotinamide… · 1XC A601 · binds TYR188, HIS191, PHE193, ARG196, GLY197, ASP219, TYR240, SER241 and 16 more
- 4O16 · Structural Basis for Resistance to Diverse Classes of NAMPT Inhibitors · 1XC A601 · binds TYR188, HIS191, PHE193, ARG196, GLY197, ASP219, TYR240, SER241 and 14 more
- 4L4L · Structural analysis of a phosphoribosylated inhibitor in complex with human nicotinamide… · 1XC A601 · binds TYR188, HIS191, PHE193, ARG196, GLY197, ASP219, TYR240, SER241 and 16 more
- 4O16 · Structural basis for resistance to diverse classes of nampt inhibitors · 1XC A601 · binds TYR188, HIS191, PHE193, ARG196, GLY197, ASP219, TYR240, SER241 and 14 more
Residues it binds most
GLY 6, ASP 6, ARG 6, TYR 6, ALA 6, ILE 6, SER 6, PRO 6, HIS 6, PHE 6 (residue and the binding sites it lines).
Found with
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