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Ligand · 1WO

1WO · (5beta)-11-hydroxyabieta-7,9(11),13-triene-6,12-dione

1WO, (5beta)-11-hydroxyabieta-7,9(11),13-triene-6,12-dione (C20 H26 O3, 314.4 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most…

Component
1WO
Formula
C20 H26 O3
Class
ligand
Structures
4
PDB entries
2

Binding sites

1WO in 4 structures; the first of them:

  • 4P0V · Crystal structure of human farnesyl diphosphoate synthase in complex with zoledronate and… · 1WO A402 · binds ALA53, GLY56, LYS57, TYR58, ASN59, ARG60, GLU93, GLN96 and 8 more
  • 4P0X · Human farnesyl diphosphate synthase in complex with Taxodione · 1WO A1001 · binds GLY56, LYS57, TYR58, ASN59, ARG60, GLU93, GLN96, LEU100 and 5 more
  • 4P0V · Crystal structure of human farnesyl diphosphoate synthase in complex with zoledronate and… · 1WO A402 · binds ALA53, GLY56, LYS57, TYR58, ASN59, ARG60, GLU93, GLN96 and 8 more
  • 4P0X · Human farnesyl diphosphate synthase in complex with taxodione · 1WO A1001 · binds GLY56, LYS57, TYR58, ASN59, ARG60, GLU93, GLN96, LEU100 and 5 more

Residues it binds most

ARG 4, LYS 6, ASN 6, ALA 4, ASP 4, GLN 4, GLU 4, GLY 4, LEU 4, PHE 4 (residue and the binding sites it lines).

Found with

  • ZOL · Zoledronic acid
  • MG · Magnesium ion

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