Ligand · 1TZ
1TZ · (2S)-2-azanyl-3-(3H-indol-3-yl)-N-[(E)-(2,4,6-trimethylphenyl)methylideneamino]propanamide
1TZ, (2S)-2-azanyl-3-(3H-indol-3-yl)-N-[(E)-(2,4,6-trimethylphenyl)methylideneamino]propanamide (C21 H24 N4 O, 348.4 g/mol), in the MolNFT structures on GenesisL1: bound in 6 records (3 PDB entries). Every binding site with its residues…
- Component
- 1TZ
- Formula
- C21 H24 N4 O
- Class
- ligand
- Structures
- 6
- PDB entries
- 3
Binding sites
1TZ in 6 structures; the first of them:
- 4KUP · Endothiapepsin in complex with 20mM acylhydrazone inhibitor · 1TZ A401 · binds ASP33, ASP35, GLY37, TYR79, GLY80, ASP81, SER83, PHE116 and 9 more
- 4LBT · Endothiapepsin in complex with 100mM acylhydrazone inhibitor · 1TZ A402 · binds ILE10, ASP11, ASP15, ALA16, ASP119, ILE122, THR223
- 4LHH · Endothiapepsin in complex with 2mM acylhydrazone inhibitor · 1TZ A401 · binds ASP33, ASP35, GLY37, TYR79, GLY80, ASP81, SER83, PHE116 and 9 more
- 4KUP · Endothiapepsin in complex with 20MM acylhydrazone inhibitor · 1TZ A401 · binds ASP33, ASP35, GLY37, TYR79, GLY80, ASP81, SER83, PHE116 and 9 more
- 4LBT · Endothiapepsin in complex with 100MM acylhydrazone inhibitor · 1TZ A402 · binds ILE10, ASP11, ASP15, ALA16, ASP119, ILE122, THR223
- 4LHH · Endothiapepsin in complex with 2MM acylhydrazone inhibitor · 1TZ A401 · binds ASP33, ASP35, GLY37, TYR79, GLY80, ASP81, SER83, PHE116 and 9 more
Residues it binds most
ASP 12, ILE 12, GLY 8, TYR 8, PHE 8, THR 10, LEU 8, SER 6, ALA 4, PRO 2 (residue and the binding sites it lines).
Found with
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