Ligand · 1QK
1QK · 3-[({3-ethyl-5-[(2S)-2-(2-hydroxyethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl}amino)methyl]-1-hydroxypyridinium
1QK, 3-[({3-ethyl-5-[(2S)-2-(2-hydroxyethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl}amino)methyl]-1-hydroxypyridinium (C21 H29 N6 O2 +1, 397.5 g/mol), in the MolNFT structures on GenesisL1: bound in 5 records (4 PDB entries). Every…
- Component
- 1QK
- Formula
- C21 H29 N6 O2 +1
- Class
- ligand
- Structures
- 5
- PDB entries
- 4
Binding sites
1QK in 5 structures; the first of them:
- 5L2W · The X-ray co-crystal structure of human CDK2/CyclinE and Dinaciclib. · 1QK A900 · binds ILE10, GLU12, GLY13, VAL18, ALA31, PHE80, GLU81, PHE82 and 10 more
- 8H4R · The Crystal Structure of CDK3 and CyclinE1 Complex with Dinaciclib from Biortus · 1QK A401 · binds GLU8, ILE10, GLY11, GLU12, GLY13, VAL18, ALA31, VAL64 and 13 more
- 8P78 · Cryo-EM structure of CAK in complex with inhibitor dinaciclib · 1QK J401 · binds LEU18, GLY19, VAL26, ALA39, LYS41, PHE91, ASP92, PHE93 and 6 more
- 5L2W · The X-ray co-crystal structure of human CDK2/CYCLINE and dinaciclib. · 1QK A900 · binds ILE10, GLU12, GLY13, VAL18, ALA31, PHE80, GLU81, PHE82 and 10 more
- 6GU6 · CDK1/CKS2 in complex with dinaciclib · 1QK A301 · binds ILE10, GLY11, GLU12, GLY13, VAL18, ALA31, LYS33, VAL64 and 13 more
Residues it binds most
ASP 5, GLU 5, LEU 5, PHE 5, ALA 5, VAL 5, GLN 4, GLY 5, LYS 5, ASN 4 (residue and the binding sites it lines).
Found with
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