GL1X · GenesisL1 explorer

Ligand · 1Q3

1Q3 · (1R,2S)-2-{[8-oxo-2-(1H-pyrazol-4-yl)-5,8-dihydropyrido[3,4-d]pyrimidin-4-yl]amino}cyclopentanecarbonitrile

1Q3, (1R,2S)-2-{[8-oxo-2-(1H-pyrazol-4-yl)-5,8-dihydropyrido[3,4-d]pyrimidin-4-yl]amino}cyclopentanecarbonitrile (C16 H15 N7 O, 321.3 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with…

Component
1Q3
Formula
C16 H15 N7 O
Class
ligand
Structures
2
PDB entries
1

Binding sites

1Q3 in 2 structures; the first of them:

  • 4K6Z · The Jak1 kinase domain in complex with compound 37 · 1Q3 A1201 · binds LEU881, GLY882, GLU883, GLY884, VAL889, ALA906, VAL938, MET956 and 12 more
  • 4K6Z · The JAK1 kinase domain in complex with compound 37 · 1Q3 A1201 · binds LEU881, GLY882, GLU883, GLY884, VAL889, ALA906, VAL938, MET956 and 12 more

Residues it binds most

GLY 2, GLU 2, LEU 2, VAL 2, ALA 2, ARG 2, ASN 2, ASP 2, MET 2, PHE 2 (residue and the binding sites it lines).

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.