GL1X · GenesisL1 explorer

Ligand · 1PU

1PU · 1-(5-oxo-2,3,5,9B-tetrahydro-1H-pyrrolo[2,1-a]isoindol-9-yl)-3-pyridin-2-yl-urea

1PU, 1-(5-oxo-2,3,5,9B-tetrahydro-1H-pyrrolo[2,1-a]isoindol-9-yl)-3-pyridin-2-yl-urea (C17 H16 N4 O2, 308.3 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its residues within 4.5…

Component
1PU
Formula
C17 H16 N4 O2
Class
ligand
Structures
4
PDB entries
2

Binding sites

1PU in 4 structures; the first of them:

  • 1GIH · Human cyclin dependent kinase 2 complexed with the CDK4 inhibitor · 1PU A501 · binds ILE10, GLU12, VAL18, ALA31, LYS33, VAL64, PHE80, GLU81 and 10 more
  • 1GII · Human cyclin dependent kinase 2 complexed with the CDK4 inhibitor · 1PU A501 · binds ILE10, VAL18, ALA31, LYS33, VAL64, PHE80, GLU81, HIS82 and 8 more
  • 1GIH · Human cyclin dependent kinase 2 complexed with the CDK4 inhibitor · 1PU A501 · binds ILE10, GLU12, VAL18, ALA31, LYS33, VAL64, PHE80, GLU81 and 10 more
  • 1GII · Human cyclin dependent kinase 2 complexed with the CDK4 inhibitor · 1PU A501 · binds ILE10, VAL18, ALA31, LYS33, VAL64, PHE80, GLU81, HIS82 and 8 more

Residues it binds most

VAL 4, ALA 4, ASP 4, GLN 4, GLU 4, HIS 4, LEU 4, PHE 4, ILE 4, LYS 4 (residue and the binding sites it lines).

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.