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Ligand · 1NR

1NR · 4-(4-{2-[(2,2-dimethylpropanoyl)amino]ethyl}piperidin-1-yl)thieno[3,2-d]pyrimidine-6-carboxamide

1NR, 4-(4-{2-[(2,2-dimethylpropanoyl)amino]ethyl}piperidin-1-yl)thieno[3,2-d]pyrimidine-6-carboxamide (C19 H27 N5 O2 S, 389.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its…

Component
1NR
Formula
C19 H27 N5 O2 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

1NR in 2 structures; the first of them:

  • 4JT8 · Crystal Structure of human SIRT3 with ELT inhibitor 28… · 1NR A402 · binds ALA146, SER149, ILE154, PRO155, ASP156, PHE157, ARG158, TYR165 and 11 more
  • 4JT8 · Crystal structure of human SIRT3 with elt inhibitor 28 [4-(4-{2-[(2,2… · 1NR A402 · binds ALA146, SER149, ILE154, PRO155, ASP156, PHE157, ARG158, TYR165 and 11 more

Residues it binds most

PHE 2, ILE 2, ASP 2, ALA 2, ARG 2, ASN 2, GLN 2, GLY 2, HIS 2, PRO 2 (residue and the binding sites it lines).

Found with

  • ZN · Zinc ion

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