Ligand · 1L8
1L8 · 8-fluoro-N-{(2R)-1-oxo-1-(pyrrolidin-1-yl)-3-[3-(trifluoromethyl)phenyl]propan-2-yl}-1,2,3,4-tetrahydroisoquinoline-6-sulfonamide
1L8, 8-fluoro-N-{(2R)-1-oxo-1-(pyrrolidin-1-yl)-3-[3-(trifluoromethyl)phenyl]propan-2-yl}-1,2,3,4-tetrahydroisoquinoline-6-sulfonamide (C23 H25 F4 N3 O3 S, 499.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB…
- Component
- 1L8
- Formula
- C23 H25 F4 N3 O3 S
- Class
- ligand
- Structures
- 2
- PDB entries
- 1
Binding sites
1L8 in 2 structures; the first of them:
- 4JLG · SETD7 in complex with inhibitor (R)-PFI-2 and S-adenosyl-methionine · 1L8 A402 · binds TYR245, HIS252, VAL255, ASP256, ASN263, GLY264, ASN265, THR266 and 10 more
- 4JLG · SETD7 in complex with inhibitor (R)-pfi-2 and S-adenosyl-methionine · 1L8 A402 · binds TYR245, HIS252, VAL255, ASP256, ASN263, GLY264, ASN265, THR266 and 10 more
Residues it binds most
TYR 4, ASN 4, GLY 4, HIS 4, SER 4, VAL 4, ASP 4, LEU 4, PRO 4, THR 4 (residue and the binding sites it lines).
Found with
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