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Ligand · 1L6

1L6 · 1-(2-hydroxyethyl)-3-(2-methylbutan-2-yl)-5-[4-(2-methyl-1H-imidazol-1-yl)phenyl]-6,7-dihydropyrazolo[4,3-e][1,4]diazepin-8(1H)-one

1L6, 1-(2-hydroxyethyl)-3-(2-methylbutan-2-yl)-5-[4-(2-methyl-1H-imidazol-1-yl)phenyl]-6,7-dihydropyrazolo[4,3-e][1,4]diazepin-8(1H)-one (C23 H28 N6 O2, 420.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry).…

Component
1L6
Formula
C23 H28 N6 O2
Class
ligand
Structures
2
PDB entries
1

Binding sites

1L6 in 2 structures; the first of them:

  • 4JIB · Crystal structure of of PDE2-inhibitor complex · 1L6 A1003 · binds TYR655, HIS656, LEU770, LEU809, ASP811, GLN812, ILE822, ILE826 and 7 more
  • 4JIB · Crystal structure of of PDE2-inhibitor complex · 1L6 A1003 · binds TYR655, HIS656, LEU770, LEU809, ASP811, GLN812, ILE822, ILE826 and 7 more

Residues it binds most

ILE 8, LEU 8, GLN 8, PHE 8, TYR 8, ASP 8, HIS 8, MET 8, SER 8, ALA 2 (residue and the binding sites it lines).

Found with

  • MG · Magnesium ion
  • ZN · Zinc ion

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