Ligand · 1HL
1HL · N-{3-[(4S,6S)-2-amino-4-methyl-6-(trifluoromethyl)-5,6-dihydro-4H-1,3-oxazin-4-yl]-4-fluorophenyl}-5-cyanopyridine-2-carboxamide
1HL, N-{3-[(4S,6S)-2-amino-4-methyl-6-(trifluoromethyl)-5,6-dihydro-4H-1,3-oxazin-4-yl]-4-fluorophenyl}-5-cyanopyridine-2-carboxamide (C19 H15 F4 N5 O2, 421.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry).…
- Component
- 1HL
- Formula
- C19 H15 F4 N5 O2
- Class
- ligand
- Structures
- 2
- PDB entries
- 1
Binding sites
1HL in 2 structures; the first of them:
- 4J1F · CRYSTAL STRUCTURE OF BACE-1 IN COMPLEX WITH 5-Cyano-pyridine-2-carboxylic acid… · 1HL A504 · binds GLY72, GLN73, GLY74, TYR75, LEU91, ASP93, GLY95, SER96 and 14 more
- 4J1F · Crystal structure of bace-1 in complex with 5-cyano-pyridine-2- carboxylic acid… · 1HL A504 · binds GLY72, GLN73, GLY74, TYR75, LEU91, ASP93, GLY95, SER96 and 14 more
Residues it binds most
GLY 2, THR 2, ASP 2, ILE 2, SER 2, TYR 2, ALA 2, ARG 2, GLN 2, GLU 2 (residue and the binding sites it lines).
Found with
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.