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Ligand · 1FR

1FR · 3-[3-chloro-5-(5-{[(1S)-1-phenylethyl]amino}isoxazolo[5,4-c]pyridin-3-yl)phenyl]propan-1-ol

1FR, 3-[3-chloro-5-(5-{[(1S)-1-phenylethyl]amino}isoxazolo[5,4-c]pyridin-3-yl)phenyl]propan-1-ol (C23 H22 Cl N3 O2, 407.9 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues…

Component
1FR
Formula
C23 H22 Cl N3 O2
Class
ligand
Structures
2
PDB entries
1

Binding sites

1FR in 2 structures; the first of them:

  • 3DB8 · Crystal structure of an activated (Thr->Asp) Polo-like kinase 1 (Plk1) catalytic domain… · 1FR A313 · binds LEU45, GLY46, LYS47, GLY48, ALA51, LYS52, CYS53, ALA66 and 11 more
  • 3DB8 · Crystal structure of an activated (thr->asp) polo-like kinase 1 (PLK1) catalytic domain… · 1FR A313 · binds LEU45, GLY46, LYS47, GLY48, ALA51, LYS52, CYS53, ALA66 and 11 more

Residues it binds most

GLY 2, LYS 2, ALA 2, ARG 2, CYS 2, GLU 2, LEU 2, ILE 2, PHE 2, SER 2 (residue and the binding sites it lines).

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