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Ligand · 1F5

1F5 · (1R,3aS,4R,5R,6R,9aR,10E)-6-({(1S,2R,4S,5R,6R,8S,9S)-5-hydroxy-2-(methoxymethyl)-9-methyl-9-[(2S)-oxiran-2-yl]-3,7,10,1 1-tetraoxatricyclo[6.2.1.0~1,6~]undec-4-yl}oxy)-1-(methoxymethyl)-4,9a-dimethyl-7-(propan-2-yl)-1,2,3,3a,4,5,6,8,9,9a-de cahydrodicyclopenta[a,d][8]annulene-1,5-diol

1F5, (1R,3aS,4R,5R,6R,9aR,10E)-6-({(1S,2R,4S,5R,6R,8S,9S)-5-hydroxy-2-(methoxymethyl)-9-methyl-9-[(2S)-oxiran-2-yl]-3,7,10,1…

Component
1F5
Formula
C33 H50 O11
Class
ligand
Structures
2
PDB entries
1

Binding sites

1F5 in 2 structures; the first of them:

  • 4IHL · Human 14-3-3 isoform zeta in complex with a diphoyphorylated C-RAF peptide and Cotylenin A · 1F5 A302 · binds ASN42, LEU43, SER45, VAL46, PHE117, LYS120, MET121, PRO165 and 8 more
  • 4IHL · Human 14-3-3 isoform zeta in complex with a diphoyphorylated C-RAF peptide and cotylenin a · 1F5 A302 · binds ASN42, LEU43, SER45, VAL46, PHE117, LYS120, MET121, PRO165 and 8 more

Residues it binds most

ILE 4, LEU 4, PRO 4, ASN 4, VAL 4, ASP 4, LYS 4, MET 4, PHE 4, SER 4 (residue and the binding sites it lines).

Found with

  • K · Potassium ion

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