GL1X · GenesisL1 explorer

Ligand · 1F0

1F0 · [(4S,5R)-2-(4-tert-butyl-2-ethoxyphenyl)-4,5-bis(4-chlorophenyl)-4,5-dimethyl-4,5-dihydro-1H-imidazol-1-yl]{4-[3-(methylsulfonyl)propyl]piperazin-1-yl}methanone

1F0, [(4S,5R)-2-(4-tert-butyl-2-ethoxyphenyl)-4,5-bis(4-chlorophenyl)-4,5-dimethyl-4,5-dihydro-1H-imidazol-1-yl]{4-[3-(methylsulfonyl)propyl]piperazin-1-yl}methanone (C38 H48 Cl2 N4 O4 S, 727.8 g/mol), in the MolNFT structures on…

Component
1F0
Formula
C38 H48 Cl2 N4 O4 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

1F0 in 2 structures; the first of them:

  • 4IPF · The 1.7A crystal structure of humanized Xenopus MDM2 with RO5045337 · 1F0 A201 · binds LEU50, TYR51, LEU53, GLY54, GLN55, ILE57, MET58, GLN68 and 6 more
  • 4IPF · The 1.7A crystal structure of humanized xenopus MDM2 with RO5045337 · 1F0 A201 · binds LEU50, TYR51, LEU53, GLY54, GLN55, ILE57, MET58, GLN68 and 6 more

Residues it binds most

GLN 2, HIS 2, ILE 2, LEU 2, TYR 2, GLY 2, MET 2, PHE 2, VAL 2 (residue and the binding sites it lines).

Found with

  • SO4 · Sulfate ion

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.