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Ligand · 1CV

1CV · (3R,5R,9R,19R,21S)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9,21-tetrahydroxy-8,8,21-trimethyl-10,14-dioxo-19-sulfanyl-2,4,6-trioxa-18-thia-11,15-diaza-3,5-diphosphatricosan-23-oic acid 3,5-dioxide

1CV, (3R,5R,9R,19R,21S)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9,21-tetrahydroxy-8,8,21-trimethyl-10,14-dioxo-19-sulfanyl-2,4,6-trioxa-18-thia-11,15-diaza-3,5-diphosphatricosan-23-oic…

Component
1CV
Formula
C27 H46 N7 O19 P3 S2
Class
ligand
Structures
2
PDB entries
1

Binding sites

1CV in 2 structures; the first of them:

  • 4I4B · HMG-CoA Reductase from Pseudomonas mevalonii complexed with NAD and intermediate… · 1CV A501 · binds ARG11, SER66, ASN67, GLU83, PRO84, SER85, ILE86, ALA88 and 25 more
  • 4I4B · Hmg-CoA reductase from pseudomonas mevalonii complexed with NAD and intermediate… · 1CV A501 · binds ARG11, SER66, ASN67, GLU83, PRO84, SER85, ILE86, ALA88 and 25 more

Residues it binds most

ALA 2, ARG 2, ASN 2, GLU 2, GLY 2, ILE 2, LEU 2, SER 2, HIS 2, LYS 2 (residue and the binding sites it lines).

Found with

  • 1CO · (3S)-3-hydroxy-3-methyl-5-sulfanylpentanoic acid
  • NAD · Nicotinamide-adenine-dinucleotide
  • SO4 · Sulfate ion
  • GOL · Glycerol

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