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Ligand · 1C7

1C7 · (7R)-8-cyclopentyl-7-ethyl-5-methyl-2-(2-phenyl-1H-imidazol-1-yl)-7,8-dihydropteridin-6(5H)-one

1C7, (7R)-8-cyclopentyl-7-ethyl-5-methyl-2-(2-phenyl-1H-imidazol-1-yl)-7,8-dihydropteridin-6(5H)-one (C23 H26 N6 O, 402.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues…

Component
1C7
Formula
C23 H26 N6 O
Class
ligand
Structures
2
PDB entries
1

Binding sites

1C7 in 2 structures; the first of them:

  • 4I6F · Selective & Brain-Permeable Polo-like Kinase-2 (Plk-2) Inhibitors that Reduce -Synuclein… · 1C7 A401 · binds LEU88, GLY89, LYS90, CYS96, ALA109, ALA110, LYS111, VAL143 and 8 more
  • 4I6F · Selective & brain-permeable polo-like kinase-2 (plk-2) inhibitors that reduce -synuclein… · 1C7 A401 · binds LEU88, GLY89, LYS90, CYS96, ALA109, ALA110, LYS111, VAL143 and 8 more

Residues it binds most

ALA 2, CYS 2, LEU 2, LYS 2, ARG 2, GLU 2, GLY 2, HIS 2, PHE 2, SER 2 (residue and the binding sites it lines).

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