1BV · (2R,6S,7E,10E,13aR,14aR,16aS)-2-{[7-methoxy-8-methyl-2-(propan-2-yloxy)quinolin-4-yl]oxy}-N-[(1-methylcyclopropyl)sulfonyl]-6-{[(1-methyl-1H-pyrazol-3-yl)carbonyl]amino}-5,16-dioxo-1,2,3,6,9,12,13,13a,14,15,16,16a-dodecahydrocyclopropa[e]pyrrolo[1,2-a][1,4]diazacyclopentadecine-14a(5H)-carboxamide

Binding sites

1BV in 6 structures; the first of them:

• 4I31 · Crystal structure of HCV NS3/NS4A protease complexed with compound 4 · 1BV A202 · binds GLN41, SER42, PHE43, TYR56, HIS57, GLY58, VAL78, ASP79 and 16 more
• 4I32 · Crystal structure of HCV NS3/4A D168V protease complexed with compound 4 · 1BV A202 · binds GLN41, SER42, PHE43, TYR56, HIS57, GLY58, VAL78, ASP79 and 15 more
• 4I33 · Crystal structure of HCV NS3/4A R155K protease complexed with compound 4 · 1BV A202 · binds GLN41, SER42, PHE43, TYR56, HIS57, GLY58, VAL78, ASP79 and 14 more
• 4I31 · Crystal structure of HCV NS3/NS4A protease complexed with compound 4 · 1BV A202 · binds GLN41, SER42, PHE43, TYR56, HIS57, GLY58, VAL78, ASP79 and 16 more
• 4I32 · Crystal structure of HCV NS3/4A D168V protease complexed with compound 4 · 1BV A202 · binds GLN41, SER42, PHE43, TYR56, HIS57, GLY58, VAL78, ASP79 and 15 more
• 4I33 · Crystal structure of HCV NS3/4A R155K protease complexed with compound 4 · 1BV A202 · binds GLN41, SER42, PHE43, TYR56, HIS57, GLY58, VAL78, ASP79 and 14 more

Residues it binds most

VAL 12, SER 12, ASP 12, ALA 12, GLY 12, PHE 12, GLN 12, ARG 10, LYS 12, HIS 12 (residue and the binding sites it lines).

Found with

• NA · Sodium ion