GL1X · GenesisL1 explorer

Ligand · 1BF

1BF · N-(6-chloro-3,3-dimethyl-3,4-dihydroisoquinolin-1-yl)-3-[4-(1H-pyrazol-4-yl)thiophen-3-yl]-L-alanine

1BF, N-(6-chloro-3,3-dimethyl-3,4-dihydroisoquinolin-1-yl)-3-[4-(1H-pyrazol-4-yl)thiophen-3-yl]-L-alanine (C21 H21 Cl N4 O2 S, 428.9 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with…

Component
1BF
Formula
C21 H21 Cl N4 O2 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

1BF in 2 structures; the first of them:

  • 4I0F · Design and Synthesis of Thiophene Dihydroisoquinolins as Novel BACE-1 Inhibitors · 1BF A504 · binds GLY72, GLN73, GLY74, LEU91, ASP93, TYR132, GLN134, GLY135 and 10 more
  • 4I0F · Design and synthesis of thiophene dihydroisoquinolins as novel bace-1 inhibitors · 1BF A504 · binds GLY72, GLN73, GLY74, LEU91, ASP93, TYR132, GLN134, GLY135 and 10 more

Residues it binds most

GLY 2, ASP 2, GLN 2, ILE 2, LYS 2, THR 2, LEU 2, PHE 2, TRP 2, TYR 2 (residue and the binding sites it lines).

Found with

  • ZN · Zinc ion

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.