GL1X · GenesisL1 explorer

Ligand · 1AZ

1AZ · 1-(3,4-dichlorobenzyl)-3,7-dimethyl-8-morpholin-4-yl-3,7-dihydro-1H-purine-2,6-dione

1AZ, 1-(3,4-dichlorobenzyl)-3,7-dimethyl-8-morpholin-4-yl-3,7-dihydro-1H-purine-2,6-dione (C18 H19 Cl2 N5 O3, 424.3 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its residues…

Component
1AZ
Formula
C18 H19 Cl2 N5 O3
Class
ligand
Structures
4
PDB entries
2

Binding sites

1AZ in 4 structures; the first of them:

  • 2WGS · Crystal structure of Mycobacterium Tuberculosis Glutamine Synthetase in complex with a… · 1AZ A501 · binds TYR129, PHE130, GLY131, ALA132, GLU133, HIS217, ASN229, TYR230 and 8 more
  • 2WHI · Crystal structure of Mycobacterium Tuberculosis Glutamine Synthetase in complex with a… · 1AZ A501 · binds TYR129, PHE130, GLY131, ALA132, GLU133, GLU214, ASN229, TYR230 and 8 more
  • 2WGS · Crystal structure of mycobacterium tuberculosis glutamine synthetase in complex with a… · 1AZ A501 · binds TYR129, PHE130, GLY131, ALA132, GLU133, HIS217, ASN229, TYR230 and 8 more
  • 2WHI · Crystal structure of mycobacterium tuberculosis glutamine synthetase in complex with a… · 1AZ A501 · binds TYR129, PHE130, GLY131, ALA132, GLU133, GLU214, ASN229, TYR230 and 8 more

Residues it binds most

ALA 36, PHE 36, TYR 36, HIS 36, GLU 36, LYS 36, ARG 36, ASN 36, GLN 36, GLY 36 (residue and the binding sites it lines).

Found with

  • CL · Chloride ion
  • P3S · L-methionine-S-sulfoximine phosphate
  • MG · Magnesium ion
  • PO4 · Phosphate ion
  • 1PE · Pentaethylene glycol

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.