GL1X · GenesisL1 explorer

Ligand · 17R

17R · (2R)-4-[4-fluoro-2-(trifluoromethyl)phenyl]-2-methyl-1-{[3-(1H-1,2,4-triazol-1-yl)phenyl]sulfonyl}piperazine

17R, (2R)-4-[4-fluoro-2-(trifluoromethyl)phenyl]-2-methyl-1-{[3-(1H-1,2,4-triazol-1-yl)phenyl]sulfonyl}piperazine (C20 H19 F4 N5 O2 S, 469.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding…

Component
17R
Formula
C20 H19 F4 N5 O2 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

17R in 2 structures; the first of them:

  • 3HFG · Crystal Structure of Human 11-beta-hydroxysteroid-dehydrogenase Bound to an… · 17R A1 · binds ILE121, THR124, SER125, LEU126, SER170, LEU171, ALA172, TYR177 and 10 more
  • 3HFG · Crystal structure of human 11-beta-hydroxysteroid-dehydrogenase bound to an… · 17R A1 · binds ILE121, THR124, SER125, LEU126, SER170, LEU171, ALA172, TYR177 and 10 more

Residues it binds most

LEU 8, TYR 8, ALA 8, SER 8, THR 8, VAL 8, GLY 8, ILE 8, PRO 8, MET 4 (residue and the binding sites it lines).

Found with

  • NAP · Nadp nicotinamide-adenine-dinucleotide phosphate

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