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Ligand · 16K

16K · 4-(2,4-dimethyl-1,3-thiazol-5-yl)-N-(3-nitrophenyl)pyrimidin-2-amine

16K, 4-(2,4-dimethyl-1,3-thiazol-5-yl)-N-(3-nitrophenyl)pyrimidin-2-amine (C15 H13 N5 O2 S, 327.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the…

Component
16K
Formula
C15 H13 N5 O2 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

16K in 2 structures; the first of them:

  • 4EK8 · Crystal structure of the cdk2 in complex with thiazolylpyrimidine inhibitor · 16K A301 · binds ILE10, GLY11, GLY13, VAL18, ALA31, LYS33, VAL64, PHE80 and 11 more
  • 4EK8 · Crystal structure of the CDK2 in complex with thiazolylpyrimidine inhibitor · 16K A301 · binds ILE10, GLY11, GLY13, VAL18, ALA31, LYS33, VAL64, PHE80 and 11 more

Residues it binds most

ALA 2, ASP 2, GLN 2, GLY 2, LEU 2, PHE 2, VAL 2, ASN 2, GLU 2, HIS 2 (residue and the binding sites it lines).

Found with

  • ACE · Acetyl group

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