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Ligand · 15M

15M · (5Z)-7-{(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl}-N-ethylhept-5-enamide

15M, (5Z)-7-{(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl}-N-ethylhept-5-enamide (C25 H37 N O4, 415.6 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site…

Component
15M
Formula
C25 H37 N O4
Class
ligand
Structures
2
PDB entries
1

Binding sites

15M in 2 structures; the first of them:

  • 2F38 · Crystal structure of prostaglandin F synathase containing bimatoprost · 15M A325 · binds TYR24, LEU54, TRP86, SER87, HIS117, SER118, PRO119, MET120 and 14 more
  • 2F38 · Crystal structure of prostaglandin F synathase containing bimatoprost · 15M A325 · binds TYR24, LEU54, TRP86, SER87, HIS117, SER118, PRO119, MET120 and 14 more

Residues it binds most

SER 2, TYR 2, PHE 2, HIS 2, LEU 2, PRO 2, TRP 2, ASN 2, MET 2, VAL 2 (residue and the binding sites it lines).

Found with

  • NAP · Nadp nicotinamide-adenine-dinucleotide phosphate

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