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Ligand · 14Z

14Z · N-ethyl-3-methyl-2-oxo-1,2,3,4-tetrahydroquinazoline-6-sulfonamide

14Z, N-ethyl-3-methyl-2-oxo-1,2,3,4-tetrahydroquinazoline-6-sulfonamide (C11 H15 N3 O3 S, 269.3 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the…

Component
14Z
Formula
C11 H15 N3 O3 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

14Z in 2 structures; the first of them:

  • 4HBW · Crystal Structure of the first bromodomain of human BRD4 in complex with a quinazoline… · 14Z A202 · binds TRP81, PRO82, PHE83, VAL87, LEU92, LEU94, TYR97, CYS136 and 5 more
  • 4HBW · Crystal structure of the first bromodomain of human BRD4 in complex with a quinazoline… · 14Z A202 · binds TRP81, PRO82, PHE83, VAL87, LEU92, LEU94, TYR97, CYS136 and 5 more

Residues it binds most

LEU 2, TYR 2, ASN 2, ASP 2, CYS 2, ILE 2, MET 2, PHE 2, PRO 2, TRP 2 (residue and the binding sites it lines).

Found with

  • K · Potassium ion
  • EDO · 1,2-ethanediol

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