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Ligand · 14M

14M · {(3S)-1-[5-(cyclohexylcarbamoyl)-6-(propylsulfanyl)pyridin-2-yl]piperidin-3-yl}acetic acid

14M, {(3S)-1-[5-(cyclohexylcarbamoyl)-6-(propylsulfanyl)pyridin-2-yl]piperidin-3-yl}acetic acid (C22 H33 N3 O3 S, 419.6 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues…

Component
14M
Formula
C22 H33 N3 O3 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

14M in 2 structures; the first of them:

  • 4HFR · Human 11beta-Hydroxysteroid Dehydrogenase Type 1 in complex with an orally bioavailable… · 14M A302 · binds ILE121, THR124, LEU126, SER170, LEU171, ALA172, TYR177, PRO178 and 9 more
  • 4HFR · Human 11BETA-hydroxysteroid dehydrogenase type 1 in complex with an orally bioavailable… · 14M A302 · binds ILE121, THR124, LEU126, SER170, LEU171, ALA172, TYR177, PRO178 and 9 more

Residues it binds most

LEU 4, TYR 4, THR 4, ALA 4, ASP 4, GLY 4, ILE 4, MET 4, PRO 4, SER 4 (residue and the binding sites it lines).

Found with

  • NAP · Nadp nicotinamide-adenine-dinucleotide phosphate

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