GL1X · GenesisL1 explorer

Ligand · 12Z

12Z · [4-amino-2-(cyclohexylamino)-1,3-thiazol-5-yl](pyridin-3-yl)methanone

12Z, [4-amino-2-(cyclohexylamino)-1,3-thiazol-5-yl](pyridin-3-yl)methanone (C15 H18 N4 O S, 302.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the…

Component
12Z
Formula
C15 H18 N4 O S
Class
ligand
Structures
2
PDB entries
1

Binding sites

12Z in 2 structures; the first of them:

  • 3RKB · CDK2 in complex with inhibitor RC-2-73 · 12Z A457 · binds ILE10, VAL18, ALA31, LYS33, VAL64, PHE80, GLU81, PHE82 and 10 more
  • 3RKB · CDK2 in complex with inhibitor rc-2-73 · 12Z A457 · binds ILE10, VAL18, ALA31, LYS33, VAL64, PHE80, GLU81, PHE82 and 10 more

Residues it binds most

ALA 2, ASP 2, GLN 2, LEU 2, LYS 2, PHE 2, VAL 2, ASN 2, GLU 2, HIS 2 (residue and the binding sites it lines).

Found with

  • EDO · 1,2-ethanediol

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.