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Ligand · 11M

11M · 1-(1'-{[3-(methylsulfanyl)-2-benzothiophen-1-yl]carbonyl}spiro[1-benzofuran-3,4'-piperidin]-5-yl)methanamine

11M, 1-(1'-{[3-(methylsulfanyl)-2-benzothiophen-1-yl]carbonyl}spiro[1-benzofuran-3,4'-piperidin]-5-yl)methanamine (C23 H24 N2 O2 S2, 424.6 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site…

Component
11M
Formula
C23 H24 N2 O2 S2
Class
ligand
Structures
2
PDB entries
1

Binding sites

11M in 2 structures; the first of them:

  • 2ZEB · Potent, Nonpeptide Inhibitors of Human Mast Cell Tryptase · 11M A244 · binds GLN87, ASP188, SER189, CYS190, GLN191, SER194, VAL212, TRP214 and 9 more
  • 2ZEB · Potent, nonpeptide inhibitors of human mast cell tryptase · 11M A244 · binds GLN87, ASP188, SER189, CYS190, GLN191, SER194, VAL212, TRP214 and 9 more

Residues it binds most

GLY 8, CYS 8, GLN 8, SER 8, ASP 8, GLU 8, PRO 8, THR 8, TRP 8, TYR 8 (residue and the binding sites it lines).

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