Ligand · 10Z

10Z · N-(4-{[(2-methoxyethyl)amino]methyl}phenyl)-6-(pyridin-4-yl)quinazolin-2-amine

10Z, N-(4-{[(2-methoxyethyl)amino]methyl}phenyl)-6-(pyridin-4-yl)quinazolin-2-amine (C23 H23 N5 O, 385.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å…

Component: 10Z
Formula: C23 H23 N5 O
Class: ligand
Structures: 2
PDB entries: 1

Binding sites

10Z in 2 structures; the first of them:

4H58 · BRAF in complex with compound 3 · 10Z A801 · binds ILE462, VAL470, ALA480, LYS482, LEU513, THR528, GLN529, TRP530 and 5 more
4H58 · Braf in complex with compound 3 · 10Z A801 · binds ILE462, VAL470, ALA480, LYS482, LEU513, THR528, GLN529, TRP530 and 5 more

Residues it binds most

ALA 2, ASP 2, CYS 2, GLN 2, HIS 2, ILE 2, LEU 2, LYS 2, PHE 2, SER 2 (residue and the binding sites it lines).

Found with

CL · Chloride ion

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