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Ligand · 10K

10K · N-(3-cyclopropyl-1H-pyrazol-5-yl)-2-[4-(thiophen-2-yl)phenyl]acetamide

10K, N-(3-cyclopropyl-1H-pyrazol-5-yl)-2-[4-(thiophen-2-yl)phenyl]acetamide (C18 H17 N3 O S, 323.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the…

Component
10K
Formula
C18 H17 N3 O S
Class
ligand
Structures
2
PDB entries
1

Binding sites

10K in 2 structures; the first of them:

  • 4EK6 · Crystal structure of the cdk2 in complex with aminopyrazole inhibitor · 10K A301 · binds GLU8, LYS9, ILE10, VAL18, ALA31, VAL64, PHE80, GLU81 and 8 more
  • 4EK6 · Crystal structure of the CDK2 in complex with aminopyrazole inhibitor · 10K A301 · binds GLU8, LYS9, ILE10, VAL18, ALA31, VAL64, PHE80, GLU81 and 8 more

Residues it binds most

ALA 2, ASP 2, GLU 2, LEU 2, PHE 2, VAL 2, GLN 2, HIS 2, ILE 2, LYS 2 (residue and the binding sites it lines).

Found with

  • ACE · Acetyl group

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