GL1X · GenesisL1 explorer

Ligand · 0WT

0WT · (1R,5S,6s)-3-[5-chloro-6-ethyl-2-(pyrimidin-5-yloxy)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]-3-azabicyclo[3.1.0]hexan-6-amine

0WT, (1R,5S,6s)-3-[5-chloro-6-ethyl-2-(pyrimidin-5-yloxy)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]-3-azabicyclo[3.1.0]hexan-6-amine (C17 H18 Cl N7 O, 371.8 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every…

Component
0WT
Formula
C17 H18 Cl N7 O
Class
ligand
Structures
2
PDB entries
1

Binding sites

0WT in 2 structures; the first of them:

  • 4GEE · Pyrrolopyrimidine inhibitors of DNA gyrase B and topoisomerase IV, part I: structure… · 0WT A301 · binds ILE45, ASN48, SER49, GLU52, VAL73, ASP75, ARG78, GLY79 and 9 more
  • 4GEE · Pyrrolopyrimidine inhibitors of DNA gyrase B and topoisomerase IV, part I: structure… · 0WT A301 · binds ILE45, ASN48, SER49, GLU52, VAL73, ASP75, ARG78, GLY79 and 9 more

Residues it binds most

VAL 2, GLY 2, ILE 2, SER 2, THR 2, ARG 2, ASN 2, ASP 2, GLU 2, PHE 2 (residue and the binding sites it lines).

Found with

  • GOL · Glycerol

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