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Ligand · 0WF

0WF · 1-cyclopentyl-6-[(1R)-1-(3-phenoxyazetidin-1-yl)ethyl]-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one

0WF, 1-cyclopentyl-6-[(1R)-1-(3-phenoxyazetidin-1-yl)ethyl]-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one (C21 H25 N5 O2, 379.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its…

Component
0WF
Formula
C21 H25 N5 O2
Class
ligand
Structures
2
PDB entries
1

Binding sites

0WF in 2 structures; the first of them:

  • 4G2J · Human pde9 in complex with selective compound · 0WF A903 · binds PHE251, HIS252, MET365, ILE403, GLU406, LEU420, LEU421, TYR424 and 6 more
  • 4G2J · Human PDE9 in complex with selective compound · 0WF A903 · binds PHE251, HIS252, MET365, ILE403, GLU406, LEU420, LEU421, TYR424 and 6 more

Residues it binds most

PHE 4, LEU 4, ALA 4, GLN 4, GLU 4, HIS 4, ILE 4, MET 4, TYR 4, VAL 4 (residue and the binding sites it lines).

Found with

  • MG · Magnesium ion
  • ZN · Zinc ion

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