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Ligand · 0W2

0W2 · 1-{(2S)-1-[(3R)-3-(2-chlorophenyl)-2-(2-fluorophenyl)pyrazolidin-1-yl]-1-oxopropan-2-yl}-3-[(1R,3S,5R,7R)-tricyclo[3.3.1.1~3,7~]dec-2-yl]urea

0W2, 1-{(2S)-1-[(3R)-3-(2-chlorophenyl)-2-(2-fluorophenyl)pyrazolidin-1-yl]-1-oxopropan-2-yl}-3-[(1R,3S,5R,7R)-tricyclo[3.3.1.1~3,7~]dec-2-yl]urea (C29 H34 Cl F N4 O2, 525.1 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records…

Component
0W2
Formula
C29 H34 Cl F N4 O2
Class
ligand
Structures
2
PDB entries
1

Binding sites

0W2 in 2 structures; the first of them:

  • 4FXY · Crystal structure of rat neurolysin with bound pyrazolidin inhibitor · 0W2 P701 · binds THR45, TYR49, LEU69, ILE72, GLU73, TYR76, ILE77, ARG80 and 13 more
  • 4FXY · Crystal structure of rat neurolysin with bound pyrazolidin inhibitor · 0W2 P701 · binds THR45, TYR49, LEU69, ILE72, GLU73, TYR76, ILE77, ARG80 and 13 more

Residues it binds most

ARG 4, ILE 4, TYR 4, LEU 4, MET 4, SER 4, ASP 4, GLU 4, GLY 4, PHE 4 (residue and the binding sites it lines).

Found with

  • ZN · Zinc ion

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