GL1X · GenesisL1 explorer

Ligand · 0SE

0SE · 2-(1-{[2-(2-aminopyrimidin-5-yl)-4-(morpholin-4-yl)pyrido[3,2-d]pyrimidin-6-yl]methyl}piperidin-4-yl)propan-2-ol

0SE, 2-(1-{[2-(2-aminopyrimidin-5-yl)-4-(morpholin-4-yl)pyrido[3,2-d]pyrimidin-6-yl]methyl}piperidin-4-yl)propan-2-ol (C24 H32 N8 O2, 464.6 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site…

Component
0SE
Formula
C24 H32 N8 O2
Class
ligand
Structures
2
PDB entries
1

Binding sites

0SE in 2 structures; the first of them:

  • 4EZL · Potent and Selective Inhibitors of PI3K-delta: Obtaining Isoform Selectivity from the… · 0SE A1201 · binds MET804, ALA805, TRP812, ILE831, LYS833, ASP836, LEU838, ASP841 and 11 more
  • 4EZL · Potent and selective inhibitors of PI3K-delta: obtaining isoform selectivity from the… · 0SE A1201 · binds MET804, ALA805, TRP812, ILE831, LYS833, ASP836, LEU838, ASP841 and 11 more

Residues it binds most

ILE 2, ASP 2, LYS 2, MET 2, ALA 2, GLU 2, LEU 2, PHE 2, THR 2, TRP 2 (residue and the binding sites it lines).

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.